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1528 Locust street, Saint Louis, Missouri (Mo), 63103 , USA (show map)
Hotel Overview

Lock in a great price now and relax with our Price Guardian working for you
Hotel prices fluctuate. Book now, we will check prices each day for you and then let you know how to re-book if an even better price becomes available.Rooms List
Setup a Price Alert for 21c Museum Hotel St Louis
Each day we'll check prices and send you an email for your selected dates at 21c Museum Hotel St Louis. If you don't have specific dates but would like to check prices for say next weekend or say next month we can check the price too.
When the hotel goes on sale you will know straight away from the daily email and be able to book with confidence that you've got excellent value.
Facilities of 21c Museum Hotel St Louis
General
Parking
Activities
Billiards
Food & Drink
Bar, Restaurant, Room service, Special diet menus (on request), Vending machine (drinks), Vending machine (snacks)
Pools and wellness
Fitness centre, Hot tub, Indoor pool, Indoor pool (all year), Massage, Spa and wellness centre
Front-desk/reception area services
24-hour front desk, ATM/cash machine on site, Concierge service, Luggage storage, Private check-in/check-out, Safety deposit box, Valet parking
Common areas
Games room, Shared lounge/TV area, Terrace
Cleaning services
Daily maid service, Dry cleaning, Laundry
Business facilities
Business centre, Meeting/banquet facilities
Miscellaneous
Air conditioning, Allergy-free room, Facilities for disabled guests, Heating, Lift, Non-smoking rooms, Non-smoking throughout, Soundproof rooms
Room facilities [ These may vary room to room ]
Air Conditioning, Alarm clock, Bath, Bath or Shower, Bathrobe, Bathroom, Cable Channels, Desk, Fireplace, Flat-screen TV, Free toiletries, Hairdryer, Heating, Iron, Linen, Pay-per-view Channels, Refrigerator, Safety Deposit Box, Seating Area, Shower, Toilet, Towels, Wardrobe/Closet
Hotel Policies
Check-In
16:00:00- hours
Check-Out
-11:00:00 hours
Cancellation / Prepayment
Cancellation, prepayment and 'book now pay later' policies vary according to room type. Please check the room conditions when selecting your room above.
Accepted credit cards
The hotel reserves the right to pre-authorise credit cards prior to arrival.
The fine print
Guests are required to show a photo identification and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply.
Traveller reviews

“Super cool hotel!”
23 Dec 2024
Breakfast was excellent! And dinner at the bar. I loved the spa facilities, it was a shame the steam room was not working at the time. Otherwise everything was fantastic! They had sparkling water on tap! I loved that! And the art gallery was a great bonus! loved it!

“Great stay, in a very beautifull place, really nice hotel with very professional personel !”
24 Sep 2024
Amazing stay, wonderfull sport facilities, great art, topnotch food, a bit hard (read impossible) to get a table in the restaurant, every evening for the six days I stayed there, the restaurant was so called full meanwhile three quarters of the tables were empty.. had to eat in the bar and that was just fine, but weird that they refuse clients in the restaurant meanwhile their resto is and often stays empty the whole time. Top food when the chef is there, when he is not there you can see the difference, the food is less well prepared. Personnel is very friendly and helping. I globally loved my stay and definitely recommend this hotel! the art everywhere is simply amazing!

“Nice rooms and helpful staff”
04 Aug 2024
We especially liked the decor, the comfy beds and the helpful staff.

“Superb”
18 Jul 2024
The design of the hotel is exceptional, The rooms are cool and beautifully furnished with complimentary lavazza coffee, the art gallery on the 1st floor was very interesting with a number of high quality exhibits.

“Wonderful team, wonderful hotel best stay I’ve had in years”
17 Jul 2024
Inspiring, different beautifully appointed. Thoughtful staff, great food, relaxed and fun.

“Good location but I should have received a credit on my credit card for staying in a room with wet c”
02 Jul 2024
1. Valet people were very nice and the front desk staff. 2. Food in the restaurant was good.

“Friendly staff, lovely hotel…”
09 Jun 2024
Really lovely. Nice staff that would go out of their way to help. Interesting art gallery!

“I must come back and eat lunch and dinner. Would love to try out the spa services too.”
21 May 2024
Breakfast was really good. Location was great, close to everything we needed for the weekend. The art museum was a hit, patio area was nice.

“Good location and a really nice hotel, great choice for a stay in St Louis”
17 May 2024
Comfortable bed, nice bar and cafe, nicely decorated and furnished,complimentary night caps were a nice touch.

“Superb”
06 Apr 2024
Definitely was a great experience. Staff was very pleasant and food was great.